Saffron : Technical documentation
Saffron stimulates libido, helps increase sperm volume, and relaxes muscles. It also helps improve erections.
Claim 2427 filed with the EFSA: "1. Stimulates libido 2. Improves erection, contributes to increased semen volume and relaxes muscles".
Claim 2038 filed with the EFSA: "Contributes to emotional balance; -Helps promote relaxation -Helps maintain a positive mood. / Used to help achieve better sleep / Used to reduce nervous tension / Used to reduce instability / Used to reduce irritability / Helps achieve better sleep / Helps reduce nervous tension / Helps reduce nervous tension / Helps reduce restlessness / Helps reduce restlessness / Helps reduce irritability / Helps reduce irritability. / Promotes the maintenance of a state of relaxation and "For mental and physical well-being / Helps maintain a good mood / Helps maintain joint mobility and flexibility."
Claim 2251 filed with the EFSA: "Helps maintain good comfort before and during the menstrual cycle."
Asr Badr Y A, Sepehran E, Del Azar A, Sadeghi H, Nouri M. The Effect of Saffron on Semen Analysis in Infertile Men with Clinical Varicocele After Varicocelectomy. Nephro-Urol Mon. 2017;9(5)
Hajizadeh Maleki B, Tartibian B, Mooren F.C, Yaghoob Nezhad F, Yaseri M. Saffron supplementation ameliorates oxidative damage to sperm DNA following a 16-week low-to-intensive cycling training in male road cyclists, Journal of Functional Foods, 2016, (21)153-166.
Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia. Phytother Res. 2011 Apr;25(4):508-16.
WHO (WORLD HEALTH ORGANIZATION). Stigma Croci (dried stigmas of Crocus sativus L.) In: WHO monographs on selected plants. Volume 3. 2007, p126.
Hosseinzadeh H, Ziaee T, Sadeghi A. The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats. Phytomedicine. 2008, 15(6-7):491-5.
Modabbernia A, Sohrabi H, Nasehi AA, Raisi F, Saroukhani S, Jamshidi A, Tabrizi M, Ashrafi M, Akhondzadeh S. Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial. Psychopharmacology (Berl). 2012, 223(4):381-8.
Mohammadzadeh-Moghadam H, Nazari SM, Shamsa A, Kamalinejad M, Esmaeeli H, Asadpour AA, Khajavi A. Effects of a Topical Saffron (Crocus sativus L) Gel on Erectile Dysfunction in Diabetics: A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Trial. J Evid Based Complementary Altern Med. 2015, 20(4):283-6.
Shamsa A, Hosseinzadeh H, Molaei M, Shakeri MT, Rajabi O. Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study. Phytomedicine. 2009, 16(8):690-3
Tadayon Najafabadi B, Farsinejad M, Shokraee K, Momtazmanesh K, Philippe D, Esalatmanesh S, Kashani L, Akhondzadeh S. Possible effects of Saffron (Crocus sativus) in the treatment of erectile dysfunction: a randomized, double-blind, placebo-controlled trial. Journal of Herbal Medicine. 2022, 32
WHO (WORLD HEALTH ORGANIZATION). Stigma Croci (dried stigmas of Crocus sativus L.) In: WHO monographs on selected plants. Volume 3. 2007, p126.