Guarana helps boost physical and mental vitality, and reduce fatigue.

Claim 2138 submitted to EFSA: "Helps maintain mental well-being / Helps maintain memory and alertness. / Helps maintain good cognitive function / Helps maintain memory and alertness. Helps maintain good cognitive function."

Claim 2062 submitted to EFSA: "Guarana helps maintain physical and mental vitality / Guarana contributes to alertness and the reduction of mental fatigue."

BRUNETON J. Pharmacognosie, Phytochimie, Plantes médicinales. 5ème édition. Paris : Edition Lavoisier Tec&Doc, 2016.

CAMPOS A.R., BARROS A.I.S, ALBUQUERQUE F.A.A., et al. Acute effects of guarana (Paullinia cupana Mart.) on mouse behaviour in forced swimming and open filed tests. Phytotherapy Research. 2005, 19(5).

DA COSTA MIRANDA V., TRUFELLI D.C., SANTOS J., et al. Effectiveness of Guarana (Paullinia cupana) for postradiation fatigue and depression: results of a pilot double-blind randomized study. The Journal of Alternative and Complementary Medicine. 2009,15(4).

GURNEY T., BRADLEY N., IZQUIERDO D. and RONCA F. Cognitive effects of guarana supplementation with maximal intensity cycling. Br J Nutr. 2023, 130(2).

HACK B., MACEDO PENNA E., TALIK T., et al. Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis. Nutrients. 2023, 15.

HASKELL C.F., KENNEDY D.O., WESNES K.A., et al. A double-blind, placebo-controlled, multidose evaluation of the acute behavioural effects of guaraná in humans. J Psychopharmacol. 2007, 21(1).

HEALTH CANADA. Natural Health Product, Cognitive function product. 2021.

KENNEDY D.O., HASKELL C.F., WESNES K.A., et al. Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacol Biochem Behav. 2004, 79(3).

KENNEDY D.O. and WIGHTMAN E.L. Mental Performance and Sport: Caffeine and Co‑consumed Bioactive Ingredients. Sports Medicine. 2022, 52(Suppl 1).

LIMA W.P., CARNEVALI L.C., EDER R., FERNANDO L., et al. Lipid metabolism in trained rats: effect of guarana (Paullinia cupana Mart.) supplementation. Clinical Nutrition. 2005,24.

PENNA E.M., HARP A., HACK B., et al. Guarana (Paullinia cupana) but Not Low-Dose Caffeine Improves Cycling Time-Trial Performance Versus Placebo. Int J Sport Nutr Exerc Metab. 2023, 34(1).

SHARIF S., GUIRGUIS A., FERGUS S. and SCHIFANO F. The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review. Brain Sci. 2021, 11(3).

WICHTL, M., & ANTON, R. Plantes thérapeutiques : tradition, pratique officinale, science et thérapeutique. Paris : Éd. Tec & Doc. 2003