Lemon balm is used to combat nervous system disorders. It is also known to reduce nervous agitation and promote relaxation. It is therefore indicated for reducing nervousness and anxiety.

Claim 2084 filed with EFSA: "Helps maintain a positive mood and good cognitive function, contributes to optimal relaxation, helps promote relaxation and mental and physical well-being, contributes to restful and calm sleep / Helps maintain a positive mood and good cognitive function."

Claim 4443 filed with EFSA: "Supports a healthy circulatory system."

Claim 4444 filed with EFSA: "Maintains the body's natural hormonal balance."

Claim 2302 filed with the EFSA: "Used to help you get better sleep" / "Used to reduce nervous tension" / "Used to reduce restlessness" / "Used to reduce irritability" / "Helps you get better sleep" / "Contributes to getting better sleep" / "Contributes to reducing restlessness" / "Contributes to reducing restlessness" / "Contributes to reducing restlessness".

ALIJANIHA F., NASERI M., AFSHARYPUOR S., et al. Heart palpitation relief with Melissa officinalis leaf extract: Double blind, randomized, placebo controlled trial of efficacy and safety. Journal of Ethnopharmacology. 2015, 164.

BANO A. HEPSOMALI P., RABBANI F., et al. The possible "calming effect" of subchronic supplementation of a standardized phospholipid carrier-based Melissa officinalis L. extract in healthy adults with emotional distress and poor sleep conditions: results from a prospective, randomized, double-blinded, placebo-controlled clinical trial. Front Pharmacol. 2023, 14.

EUROPEAN SCIENTIFIC COOPERATIVE ON PHYTOTHERAPY (ESCOP). ESCOP monographs. 2003.

GHAZIZADEH J., SADIGH-ETEGHAD S., MARX W., et al. The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis. Phytotherapy Research. 2021.

HEYDARI N., DEHGHANI M., EMAMGHOREISHI M. and AKBARZADEH M. Effect of Melissa officinalis capsule on the mental health of female adolescents with premenstrual syndrome: a clinical trial study. International Journal of Adolescent Medicine and Health. 2018.

KENDA M., KOČEVAR GLAVAČ N., NAGY M. and SOLLNER DOLENC M. Medicinal Plants Used for Anxiety, Depression, or Stress Treatment: An Update. Molecules. 2022, 27.

KENNEDY D.O., WAKE G., SAVELEV S., et al. Modulation of Mood and Cognitive Performance Following

Acute Administration of Single Doses of Melissa Officinalis (Lemon Balm) with Human CNS Nicotinic and Muscarinic Receptor-Binding Properties. Neuropsychopharmacology. 2003, 28.

KENNEDY D.O., LITTLE W., SCHOLEY A.B., et al. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004, 66.

SCHOLEY A., GIBBS A., NEALE C., et al. Anti-Stress Effects of Lemon Balm-Containing Foods. Nutrients.2014, 6.

ŚWIĄDER K., STARTEK K., WIJAYA C.H. The therapeutic properties of Lemon balm (Melissa officinalis L.): Reviewing novel findings and medical indications. Journal of Applied Botany and Food Quality. 2019, 92.

YOUNG YOO D., CHOI J.H., KIM W., et al. Effects of Melissa officinalis L. (Lemon Balm) Extract on Neurogenesis Associated with Serum Corticosterone and GABA in the Mouse Dentate Gyrus. Neurochem Res. 2011, 36.